There are apparently areas in the retina that could indicate changes in mild Alzheimer's disease (AD). An international research team published an article on this in the journal Nature.

Scientists examined the differences in ten retinal layers between 19 patients with mild Alzheimer's disease (AD) and a control group of 24 subjects. The mean thickness of each individual layer was compared. The outer segment layer showed significant thinning in patients with AD. When the layers were compared point by point, patients with AD showed statistically significant thinning in irregular regions of the entire retina and nerve fiber, ganglion cell, inner nuclear, and outer segment layers compared to the control group. These findings may have future implications for improving diagnostic methods for AD.
The full article can be found here:
http://dx.doi.org/10.1038/s41598-019-49353-0
