The decision by the Joint Federal Committee (G-BA) of February 19, 2026, to classify the additional benefit of Lecanemab as ‚not proven‘ confirms the skepticism of the digiDEM project management regarding the clinical relevance of this therapy. While the only study available so far on Lecanemab shows a statistically significant difference between the drug and a placebo at the end of the study...
The new Alzheimer's drug Lecanemab is raising great hopes for people with dementia and their caregivers. But which patient groups and how many affected individuals in Germany meet the criteria for treatment with Lecanemab? This essential question is a significant reason for us to dedicate another issue of our special newsletter to...
The new Alzheimer's drug Lecanemab is raising great hopes for people with dementia and their caregivers. Very recently, a panel of experts from the European Medicines Agency (EMA) recommended the new active ingredient for treatment – subject to strict conditions. But which patient groups meet the requirements for treatment with Lecanemab? This...
In recent weeks, we have informed you in several parts of our special newsletter SCHLAGLICHT – Medications for Dementia about new dementia drugs and challenges in everyday care. You can reread all published issues at any time in our digiDEM Bavaria newsletter archive: https://digidem-bayern.de/newsletter-archiv/. In the seventh and final issue of our special newsletter SCHLAGLICHT – Medications for Dementia, Michael...
In the sixth edition of our special newsletter SCHLAGLICHT – New Medications Against Dementia, Lisa Laininger, research associate at digiDEM Bayern, discusses the publication by Dr. Jeffrey L. Cummings of the University of Nevada Las Vegas and his colleagues, titled Lecanemab: Appropriate Use Recommendations, in the professional journal The Journal of Prevention of Alzheimer’s…
In the fifth edition of our special newsletter, SCHLAGLICHT – New Drugs for Dementia, Anne Keefer, a research associate at digiDEM Bayern, discusses the publication by an international group of researchers led by Prof. Alberto J. Espay of the University of Cincinnati. In the article titled "Recalibrating the Risk-Benefit Profiles of Lecanemab..."
Echte Hilfe für Betroffene oder medialer Hype – was können wir von den neuen Medikamenten zur Behandlung der Alzheimer-Erkrankung wirklich erwarten? Weltweit führen Fachexperten kontroverse Diskussionen über die sogenannten monoklonalen Antikörper, die für die Behandlung von leichten kognitiven Beeinträchtigungen und Alzheimer-Demenz vorgesehen sind. Mit den Fakten aus der Forschung werden …
Die sogenannte Amyloid-Hypothese hat die Alzheimerforschung über Jahrzehnte hinweg maßgeblich geprägt und zur Entwicklung der ersten Antikörpertherapien geführt. Trotz dieser Fortschritte bleiben die klinischen Erfolge begrenzt, was zunehmend Fragen zur Wirksamkeit und zum tatsächlichen Nutzen dieser Therapien aufwirft. In unserem Webinar hat Prof. Dr. Christian Behl, einer der international renommiertesten …
In the fourth edition of our new special newsletter SCHLAGLICHT – New Drugs for Dementia, Florian Weidinger, research associate at digiDEM Bayern, deals with the publication "The affordability of lecanemab, an amyloid-targeting therapy for Alzheimer’s disease: an EADC-EC viewpoint" by the research team led by Professor Linus Jönsson from the Karolinska Institutet in Sweden. In the journal The Lancet…
In the third issue of our new special newsletter "SCHLAGLICHT – New Medications for Dementia," Dr. Nikolas Dietzel, a research associate at digiDEM Bayern, discusses the publication by scientists from Europe, the USA, and Australia, led by Professor Poul F. Høilund-Carlsen from Odense University Hospital in Denmark. In the article titled "Donanemab, another anti-Alzheimer’s…"
